A method of and system for calcium scoring of coronary arteries

A method of automatically determining a calcium score for at least one coronary artery is disclosed. The method comprises receiving cardiac non-contrast CT data indicative of a cardiac non-contrast CT scan carried out on a patient, analysing the cardiac non-contrast CT data in a calcified components identifier to detect candidate coronary artery calcified components, and analysing cardiac non-contrast CT data associated with the candidate coronary artery calcified components using a radiomics analyser to determine radiomic characteristics of the candidate coronary artery calcified components. The method also comprises applying machine learning to the determined radiomic characteristics associated with each candidate coronary artery calcified component to identify any calcifications that are located on a coronary artery, analysing the cardiac non-contrast CT data to identify at least one body component in the cardiac non-contrast CT data not associated with a coronary artery of the patient, and using the identified at least one body component in the cardiac non-contrast CT data to remove or avoid misclassification of calcifications on a coronary artery that are located on the at least one identified body component.