Fibrous composite material

A fibrous composite material comprising a non-fibrous component having a water content of less than 10wt%; and a fibrous component comprising a porous scaffold of a plurality of electrospun polymeric fibres; wherein the non-fibrous component is a linear or branched, water-soluble, synthetic or natur...

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Bibliographische Detailangaben
Hauptverfasser: Mehrie Behbehani, Teodor-Matei Cirstea, Gianpaolo Bruti, Marco Thio, Robert James McKean
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A fibrous composite material comprising a non-fibrous component having a water content of less than 10wt%; and a fibrous component comprising a porous scaffold of a plurality of electrospun polymeric fibres; wherein the non-fibrous component is a linear or branched, water-soluble, synthetic or natural polymer dispersed within the porous scaffold; and wherein at least 50% by weight of the fibrous composite material is the fibrous component. A process for making said fibrous composite material comprising simultaneous depositing a non-fibrous component while electrospinning a plurality of polymeric fibres to form the fibrous composite material on a collector. The fibrous composite material is useful in therapy, for instance, as a synthetic or substitute amniotic membrane. It may be used in the prevention and/or treatment of ocular defects and disorders, preferably a corneal defect or disorder. It may also be used in the prevention and/or treatment of various trauma induced and chronic wounds.