Anti-Coronavirus antibodies and methods of use

At least 32 different antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2 are claimed. One of the antibody's specifically claimed is FAB55...

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Hauptverfasser: Wei Shi, Yi Zhang, Qing Chai, Lingshu Wang, Christopher Carl Frye, Ganapathy Gopalrathnam, Jeffrey Streetman Boyles, Kizzmekia Corbett, Kevin Jepson, Anna Pustilnik, Kathryn Westendorf, John Mascola, Wing-pui Kong, Bryan Edward Jones, Julian Davies, John Michael Sauder, Barney Graham, Krithika Muthuraman, Ester Falconer, Julie Ledgerwood, Stefanie Zentelis, Olubukola Abiona, Jôrg Hendle, Denisa Foster
Format: Patent
Sprache:eng
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Zusammenfassung:At least 32 different antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2 are claimed. One of the antibody's specifically claimed is FAB555 which is also known as LY-CoV555 and a specific epitope for this antibody to bind to was identified.