Methods and compositions that utilize transciptome sequencing data in machine learning-based classification

Provided herein are methods and systems for producing a modified biological dataset by flagging or removing a nucleic acid sequence from the biological dataset that is assigned a noise-call to produce the modified biological dataset. The noise-call may be based on comparing a gene expression level,...

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Hauptverfasser: Zhanzhi Hu, Su Yeon Kim, Giulia C Kennedy, Kevin Travers, Sean P Walsh, Jing Huang
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided herein are methods and systems for producing a modified biological dataset by flagging or removing a nucleic acid sequence from the biological dataset that is assigned a noise-call to produce the modified biological dataset. The noise-call may be based on comparing a gene expression level, sequence information, or a combination thereof with a nucleic acid sequence of a control sample.