Sample preparation system and cartridge

A sample preparation cartridge for use with a sample preparation device is described. The cartridge comprises a housing defining plural separate segments arranged around a central axis of the housing, said segments containing analytes and/or beads or capture filters in use; and a moveable head arranged to rotate around said central axis and lower towards, or raise from, a desired segment when it has been rotated to be positioned above the desired segment in use. The moveable head comprises a pipette tip and the pipette tip comprises a reservoir section capable of supporting fluids, and a nozzle section capable of dispensing and aspirating fluids from the segments; wherein the pipette tip is configured to pneumatically connect to a programmable control system for providing positive and negative airflow and the pipette tip is arranged to transfer, in use, analytes and/or beads or capture filters from one segment to another in order to prepare a sample for analysis.