Phytocannabinoids in the treatment of cancer

A combination of the phytocannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD) together with temozolomide is disclosed for use in the treatment of a glioma, wherein the THC and CBD are present in a ratio of approximately 1:1 (THC:CBD) and preferably wherein the dose level of the phytocannab...

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Hauptverfasser: Luciano De Petrocellis, Angelo Antonio Izzo, Aniello Schiano Moriello, Manuel Guzman Pastor, Lesley Ann Ford, Colin Stott, Daniela Parolaro, Ruth Alexandra Ross, Stephen Wright, Sharon Anavi-Goffer, Sofia Torres, Paola Massi, Francesca Borelli, Vincenzo Di Marzo, Etienne De Meijer, Gabriella Aviello, Alessia Ligresti, Guillermo Velasco, Mar Lorente, Alan Sutton, David Potter, Geoffrey Guy, Tetsuro Kikuchi
Format: Patent
Sprache:eng
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Zusammenfassung:A combination of the phytocannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD) together with temozolomide is disclosed for use in the treatment of a glioma, wherein the THC and CBD are present in a ratio of approximately 1:1 (THC:CBD) and preferably wherein the dose level of the phytocannabinoids and/or the temozolomide is sub-effective if used alone