Zoned exhaust system

A catalytic article having a flow-through substrate having an inlet, an outlet, and an axial length; an SCR zone containing a first SCR catalyst; and an oxidation zone containing (a) a separate ASC zone and a DOC zone or (b) a mixed ASC and DOC zone, where the oxidation zone contains a PGM-containing ammonia oxidation catalyst (AMOX) and a PGM-containing DOC catalyst, the SCR zone is positioned on the substrate from the inlet end and extends less than the axial length of the substrate from the inlet, the DOC zone or the mixed ASC and DOC zone is position on the substrate from the outlet end, and when the DOC zone is present, the ASC zone is located between the SCR zone and the DOC zone. In other catalytic articles, the ASC zone further comprises a DEC catalyst. The ASC zone may be a bi-layer of an AMOX catalyst and a first or second SCR catalyst. An exhaust system with the catalytic article and a method of using the catalytic articles in an SCR process, where the amount of ammonia slip is reduced, are also described.