Fitting with microprotrusions for coupling capillary to chromatography column

A fitting (100) for coupling a capillary (102, fig 2) to another component (330, fig 6) of a fluidic device (300, fig 6), comprises a ferrule (106) configured for enclosing a front part of the capillary and for contributing to a fluidic sealing between the fitting and the other component. A ferrule chuck (108) is provided for enclosing a back part of the capillary, and a housing (104) is provided for accommodating at least a part of the ferrule chuck and for pushing the ferrule chuck against the ferrule. A microstructure is formed as multiple microprotrusions (120) on at least a part of a surface of the ferrule chuck for generating, upon tightening the fitting at the other component, a form fit with the enclosed back part of the capillary over a contact area between the ferrule chuck and the capillary. The other component may be a chromatography column.