Implantable medical device comprising first and second biodegradable polymers
A self-expanding medical implant, for placement within a lumen or cavity of a patient, comprises a tubular structure and is designed to be low-profile. The tubular structure comprises a first biodegradable polymer and a second biodegradable polymer, wherein the second polymer at least partially coat...
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Zusammenfassung: | A self-expanding medical implant, for placement within a lumen or cavity of a patient, comprises a tubular structure and is designed to be low-profile. The tubular structure comprises a first biodegradable polymer and a second biodegradable polymer, wherein the second polymer at least partially coats the tubular structure. The device has a first diameter greater than 2.5 mm, and the device recovers to at least 80% of the first diameter after being crimped to a diameter that is between 1.8 mm and 2.5 mm. Preferably, the first polymer comprises at least one strand with a modulus of elasticity greater than 1GPa. The second polymer may be characterised by a percent elongation to break that is greater than 150°C at body temperature (37°C). The second polymer can increase the mass of the tubular structure by at least 20 percent. Suitably, the first polymer comprises poly(lactic acid co-glycolic acid), whilst the second polymer may be selected from: poly(lactic acid-co-caprolactone), poly(glycolide-co-caprolactone), poly trimethylene carbonate and poly(lactic acid-co-dioxanone). A third polymer can coat the second polymer, wherein a therapeutic agent can be included within the third polymer. |
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