Compounds having Hsp90 inhibitory activity

Compounds having Hsp90 inhibitory activity

Compounds of general formula (I): or a stereoisomers, tautomers, pharmaceutically acceptable salts, or prodrugs thereof, wherein R1, R2, R3, R4, R5, R6, R8 and R9 are as defined herein, are useful for the treatment of cancers and other proliferative diseases. Also shown is a process for the preparat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: THOMAS HESTERKAMP, OLIVER ROBIN BARKER, OWEN CLIFFORD MATHER, MARK WHITTAKER, CHRISTOPHER JOHN YARNOLD, STEPHEN MARTIN COURTNEY
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compounds of general formula (I): or a stereoisomers, tautomers, pharmaceutically acceptable salts, or prodrugs thereof, wherein R1, R2, R3, R4, R5, R6, R8 and R9 are as defined herein, are useful for the treatment of cancers and other proliferative diseases. Also shown is a process for the preparation of compounds of formula (I).