Mucoadhesive granule formulations

Mucoadhesive granules comprise a) carbomer and/or a salt thereof ; and b) an inert filler. The granules can further comprise an active agent suitable for sustained release into the gastrointestinal tract or for targeted delivery to the gastrointestinal mucosa. Carbomers are particularly commercially...

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Bibliographische Detailangaben
Hauptverfasser: IAN GORDON JOLLIFFE, PAUL A DICKSON, WILLIAM PEERS, PETER WILLIAM DETTMAR, FRANK C HAMPSON
Format: Patent
Sprache:eng
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Zusammenfassung:Mucoadhesive granules comprise a) carbomer and/or a salt thereof ; and b) an inert filler. The granules can further comprise an active agent suitable for sustained release into the gastrointestinal tract or for targeted delivery to the gastrointestinal mucosa. Carbomers are particularly commercially available "Carbopols". Active agent is e.g. for treatment of gastrointestinal disorders associated with H. Pylori infections.