7-Diazo-beta-lactam derivatives

Novel 7-diazo-1,1-dioxo-cephem-4-ketones are converted to 1,1-dioxo-cephem-4-ketones substituted at C-7 which are potent protease inhibitors, in particular human leukocyte elastase (HLE) inhibitors.

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Hauptverfasser: ETTORE PERRONE, MARCO ALPEGIANI, PIERLUIGI BISSOLINO
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Sprache:eng
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creator ETTORE PERRONE
MARCO ALPEGIANI
PIERLUIGI BISSOLINO
description Novel 7-diazo-1,1-dioxo-cephem-4-ketones are converted to 1,1-dioxo-cephem-4-ketones substituted at C-7 which are potent protease inhibitors, in particular human leukocyte elastase (HLE) inhibitors.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 7-Diazo-beta-lactam derivatives
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