PROCESS FOR THE FILM-COATING OF PHARMACEUTICAL COMPOSITIONS WITH POLYMER DISPERSIONS

PURPOSE: To advantageously carry out film coating of a gastric acid resistant agent and to simplify cleaning of an apparatus, by suspending a pigment in a coating solution composed of an aqueous polymer dispersion using a specific film-forming material and dissolving a specific amount of xanthan gum...

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Hauptverfasser: JANOS TOMBOR, MARIA KIRALY, DENES BEZZEGH, PAL FEKETE
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creator JANOS TOMBOR
MARIA KIRALY
DENES BEZZEGH
PAL FEKETE
description PURPOSE: To advantageously carry out film coating of a gastric acid resistant agent and to simplify cleaning of an apparatus, by suspending a pigment in a coating solution composed of an aqueous polymer dispersion using a specific film-forming material and dissolving a specific amount of xanthan gum in a next step. CONSTITUTION: An agent is coated with a film through a step for suspending a pigment (e.g. talc or titanium dioxide) in a coating solution constituted of an aqueous polymer dispersion using an aqueous latex dispersion composed of a copolymer of ethyl acrylate, methacrylic acid or ethyl acrylate and methyl methacrylate as a film-forming material and a step for dissolving 0.05-0.5% of xanthan gum based on the total amount in the coating solution. Preferably, a mixture of ethyl acrylate and methacrylic acid in a ratio of 1:1, having about 250,000 (relative) molecular weight is used as the polymer dispersion and 0.1-0.2% of xanthan gum is added based on the total of the coating solution.
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CONSTITUTION: An agent is coated with a film through a step for suspending a pigment (e.g. talc or titanium dioxide) in a coating solution constituted of an aqueous polymer dispersion using an aqueous latex dispersion composed of a copolymer of ethyl acrylate, methacrylic acid or ethyl acrylate and methyl methacrylate as a film-forming material and a step for dissolving 0.05-0.5% of xanthan gum based on the total amount in the coating solution. Preferably, a mixture of ethyl acrylate and methacrylic acid in a ratio of 1:1, having about 250,000 (relative) molecular weight is used as the polymer dispersion and 0.1-0.2% of xanthan gum is added based on the total of the coating solution.</abstract><oa>free_for_read</oa></addata></record>
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subjects ADHESIVES
CHEMICAL PAINT OR INK REMOVERS
CHEMISTRY
COATING COMPOSITIONS, e.g. PAINTS, VARNISHES ORLACQUERS
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
CORRECTING FLUIDS
DYES
FILLING PASTES
HUMAN NECESSITIES
HYGIENE
INKS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
ORGANIC MACROMOLECULAR COMPOUNDS
PAINTS
PASTES OR SOLIDS FOR COLOURING OR PRINTING
POLISHES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
USE OF MATERIALS THEREFOR
WOODSTAINS
title PROCESS FOR THE FILM-COATING OF PHARMACEUTICAL COMPOSITIONS WITH POLYMER DISPERSIONS
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