SUSTAINED RELEASE PHARMACEUTICAL DOSAGE UNITS

SUSTAINED RELEASE PHARMACEUTICAL DOSAGE UNITS

A sustained release pharmaceutical formulation is disclosed having the capability of a linear rate of drug release over a significant period (e.g. at least 20 hours). The formulation essentially comprises a shaped, solid formulation containing a drug and a non-cross-linked hydrophilic polymer which...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: MICHAEL GORDON BROOK
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A sustained release pharmaceutical formulation is disclosed having the capability of a linear rate of drug release over a significant period (e.g. at least 20 hours). The formulation essentially comprises a shaped, solid formulation containing a drug and a non-cross-linked hydrophilic polymer which constitutes the binder for the formulation, said polymer having a swell factor between about 50 and 250 % such that when the formulation is contacted with body fluid it swells and becomes soft and rubbery but retains its integrity.