PYRIDYL-ISOQUINOLINONE DERIVATIVES

The isoquinoline derivatives represented by the following general formula (I) are useful as cardiotonics having high cardiotonic activity and low toxicity: (I) where R1 represents a lower C1-C4 alkyl group or cyclopropyl group, R2 represents formyl group, lower C1-C4 alkanoyl group and benzoyl group...

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Hauptverfasser:	TATSUO KAIHO, SEITARO KAJIYA, MAKOTO HIRAYAMA, MASAHIKO MARUYAMA, KENGO OTSUKA
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The isoquinoline derivatives represented by the following general formula (I) are useful as cardiotonics having high cardiotonic activity and low toxicity: (I) where R1 represents a lower C1-C4 alkyl group or cyclopropyl group, R2 represents formyl group, lower C1-C4 alkanoyl group and benzoyl group, lower C1-C4 alkyl group, lower C1-C4 alkenyl group, lower C1-C4 hydroxy substituted alkyl group, C1-C4 perfluoroalkyl group and R3 represents 4-pyridyl group or 2-pyridyl group respectively, and the therapeutically acceptable salts thereof are also useful as cardiotonics.