MEDICINAL COMPOSITION FOR THE TREATMENT OR PREVENTION OF ACNE BY ORAL ADMINISTRATION

PCT No. PCT/FR85/00011 Sec. 371 Date Jul. 11, 1985 Sec. 102(e) Date Jul. 11, 1985 PCT Filed Jan. 24, 1985 PCT Pub. No. WO85/03226 PCT Pub. Date Aug. 1, 1985.This composition contains, by way of main active principle, in a pharmaceutically acceptable carrier, at least one substance belonging to the carotenoid family and chosen, in particular, from the group consisting of alpha -carotene, delta -carotene, gamma -carotene, +62, beta -carotene-4,4'-dione, ethyl 8'-apo- beta -caroten-8'-oate, beta -apo-8'-carotenal, psi , psi -carotene, psi , psi -carotene-16,16'-diol and psi , psi -caroten-16-ol. This composition preferably contains from 0.001 to 10% by weight of active principle relative to the total weight of the composition and takes the form of a suspension, tablets or gelatin capsules. The pharmacological activity of this drug is an activity which inhibits comedo formation, the latter being due to an irritation caused by an excess of lipid oxide (oxidized squalene).