RIFAMYCINS AND THEIR PREPARATION

RIFAMYCINS AND THEIR PREPARATION

1276482 Rifamycins GRUPPO LEPETIT SpA 5 Jan 1971 509/71 Addition to 1226050 Heading C2A The invention concerns rifamycins of general formula wherein R is t-butyl or benzyl, R1 is C 1 to C 8 alkyl, aralkyl, aryl or hydrogen and X is hydrogen or acetyl. A process for preparing the above rifamycins com...

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1. Verfasser: NICOLA MAGGI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:1276482 Rifamycins GRUPPO LEPETIT SpA 5 Jan 1971 509/71 Addition to 1226050 Heading C2A The invention concerns rifamycins of general formula wherein R is t-butyl or benzyl, R1 is C 1 to C 8 alkyl, aralkyl, aryl or hydrogen and X is hydrogen or acetyl. A process for preparing the above rifamycins comprises treating a Mannich base of general formula wherein R, R1 and X are as above, with a C 1 to C 8 alkanoic acid, in an inert anhydrous solvent and an inert atmosphere.