Process for the preparation of 16-alkyl-pregnadiene compounds

Process for the preparation of 16-alkyl-pregnadiene compounds

Novel 16a (C1- 4 alkyl) - 3,20 - diketo - D 4,6-pregnadienes are prepared by oxidation of the corresponding D 4-compounds with a quinone having an oxidation-reduction potential of less than - 0.5 v. The novel steroids are stated to have progestative, pregnancy-maintaining and gonadinhibiting propert...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HEWETT COLIN LESLIE, WOODS GILBERT FREDERICK
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
STEROIDS
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:Novel 16a (C1- 4 alkyl) - 3,20 - diketo - D 4,6-pregnadienes are prepared by oxidation of the corresponding D 4-compounds with a quinone having an oxidation-reduction potential of less than - 0.5 v. The novel steroids are stated to have progestative, pregnancy-maintaining and gonadinhibiting properties, and they may be made up into pharmaceutical compositions for oral or parenteral administration with suitable carriers.