Prednisone preparation

The invention comprises a process for producing prednisone by microbiological dehydrogenation of cortisone acetate with simultaneous or subsequent deacetylation by means of a different micro - organism. Micro-organisms specified are, for the dehydrogenation step, Corynebacterium simplex and Mycobact...

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Hauptverfasser:	SUVOROV NICKOLAI NICKOLAECIH, NIKOV NICKOLIA ALEXAND ROVICH KRASIL, EVIAGINTSEVA IRINA SAMOLOVNA, GUSAKOVA EKATERINA GRIGOR 'EVNA, LESTROVAYA NINA NICKOLAEVNA, OLEINIK DINA MIKHAILOVNA, SKRIABIN GEORGY KONSTANTINOVICH, SEVERINA LUDMILA OLEGOVNA, GRINIUK TAT 'IANA IVANOVNA, BAICHIKOV ALEKSEI GAVRILOVICH, KOSHCHEENKO KIRA ALEXANDROVNA, SOKOLOVA LYDIA VASIL 'EVNA, RYZHKOVA VALENTINE MAXIMOVNA
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention comprises a process for producing prednisone by microbiological dehydrogenation of cortisone acetate with simultaneous or subsequent deacetylation by means of a different micro - organism. Micro-organisms specified are, for the dehydrogenation step, Corynebacterium simplex and Mycobacterium globiforme 193 and, for the deacetylation step, Bacillus megatherium.