FORME ORALE MULTIPARTICULAIRE A LIBERATION IMMEDIATE D'AU MOINS UN COMPOSE ACTIF, COMPRENANT DES PARTICULES ENROBEES RESISTANTES AU BROYAGE

An oral dosage form for the immediate release of at least one active compound, comprising coated particles consisting of a non-monocrystalline core containing said active compound and coated with at least one coating layer, said coating layer comprising (A) at least 15% by weight of water-insoluble...

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Hauptverfasser: CASTAN CATHERINE, DAVIAUD-VENET ANNE-SOPHIE
Format: Patent
Sprache:fre
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Zusammenfassung:An oral dosage form for the immediate release of at least one active compound, comprising coated particles consisting of a non-monocrystalline core containing said active compound and coated with at least one coating layer, said coating layer comprising (A) at least 15% by weight of water-insoluble polymer and (B) at least 40% by weight of polymer soluble in a 0.1N hydrochloric acid solution, the weight ratio polymer B/polymer A being comprised between 85/15 and 50/50, said coating layer representing at least 30% by weight of the total weight of said coated particles.