PROCEDE DE PREPARATION DE DERIVES DE 3-CETO-BENZOFURANE

PROCEDE DE PREPARATION DE DERIVES DE 3-CETO-BENZOFURANE

The invention relates to a method for preparing 3-keto-benzofurane derivatives of the general formula: Formula (I), where R is an alkyl or aryl group, R1 is hydrogen or an alkyl or aryl group, and R2 is a substituted alkyl or phenyl group. Said preparation method involves coupling a derivative of Fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BAILLY FREDERIC, VAYRON PHILIPPE, PRIEM THOMAS
Format: Patent
Sprache:fre
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention relates to a method for preparing 3-keto-benzofurane derivatives of the general formula: Formula (I), where R is an alkyl or aryl group, R1 is hydrogen or an alkyl or aryl group, and R2 is a substituted alkyl or phenyl group. Said preparation method involves coupling a derivative of Formula III, where X is chlorine, bromine, or iodine or a sulfonate grouping: Formula (III) with a sulfonamide derivative of the formula R-SO2-NH2 in the presence of a basic agent and a catalytic system formed of a complex between a palladium compound and a ligand.