COLLE LYOPHILISEE A BASE DE COLLAGENE ET SON UTILISATION POUR LA FABRICATION DE PROTHESES COLLANTES

A glue comprising a mixture of collagen and a crosslinking agent with at least one aldehyde functional group, which is not a polysaccharide or oxidated polyaldehydic biodegradable macromolecular mucopolysaccharide of natural origin and/or collagen so modified as to present at least on aldehyde group...

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Bibliographische Detailangaben
Hauptverfasser: HERBAGE BENJAMIN, RAGARU BERNARD
Format: Patent
Sprache:fre
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Zusammenfassung:A glue comprising a mixture of collagen and a crosslinking agent with at least one aldehyde functional group, which is not a polysaccharide or oxidated polyaldehydic biodegradable macromolecular mucopolysaccharide of natural origin and/or collagen so modified as to present at least on aldehyde group, which is not a collagen modified by oxidative cleaving which is in a lyophilized form. Independent claims are included for (1) An adhesive prosthesis comprising a prosthetic material associated with the claimed glue; (2) a prosthesis additionally comprising on one face a non-stick film consisting of crosslinked and functionalized hyaluronic acid; (3) a method of preparing the claimed prosthesis by preparing the glue, pouring it onto the material, subjecting the whole to lyophilization and optionally coating one face with a crosslinked and functionalized hyaluronic acid gel, allowing to dry, optionally subjecting to re-lyophilization and/or stoving and finally sterilizing .