Associations of deoxyfructosazine and a peroxisome-proliferating gamma-activated receptor agonist antidiabetic agent have a synergistic activity in the treatment of type 2 diabetes
An association of deoxyfructosazine (2-((1R,2S,3R)(1,2,3,4-tetrahydroxybutyl)-5-(2'S,3'R)(2',3',4'-trihydr oxybutyl pyrazine)) (I) and a peroxisome-proliferating gamma-activated receptor (PPAR psi ) agonist antidiabetic agent (II) is new. Independent claims are also included...
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Zusammenfassung: | An association of deoxyfructosazine (2-((1R,2S,3R)(1,2,3,4-tetrahydroxybutyl)-5-(2'S,3'R)(2',3',4'-trihydr oxybutyl pyrazine)) (I) and a peroxisome-proliferating gamma-activated receptor (PPAR psi ) agonist antidiabetic agent (II) is new. Independent claims are also included for (1) pharmaceutical compositions (I) and (II); and (2) their use in the prevention and/or treatment of type 2 diabetes and its complications.
La présente invention concerne l'association de déoxyfructosazine et d'un antidiabétique agoniste du récepteur gamma-activé par le proliférateur de peroxisome (PPARy), les compositions pharmaceutiques contenant cette association et leur utilisation dans la prévention et/ ou le traitement du diabète de type 2 et ses complications. |
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