UTILISATION DE DERIVES HETEROAROMATIQUES ET TRICYCLIQUES DU 1,4-DIHYDRO-1,4-DIOXONAPHTALENE, NOUVEAUX COMPOSES OBTENUS ET LEUR APPLICATION EN THERAPEUTIQUE

The therapeutical use of tricyclic nitrogen-containing derivatives and pharmaceutically acceptable salts thereof having general formula (I), for treating diseases related to venous function deficiency and/or inflammatory oedema, is disclosed. In general formula (I), A is a sulphur or oxygen atom or...

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Hauptverfasser: DESQUAND BILLIALD STEPHANIE, BOUTHERIN FALSON ODILE, FAVROU ANITA, YANNIC ARNOULT SYLVIE, FINET MICHEL, TEMBO NORBERT OLIVIER, TORREGROSA JEAN LUC
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Sprache:fre
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Zusammenfassung:The therapeutical use of tricyclic nitrogen-containing derivatives and pharmaceutically acceptable salts thereof having general formula (I), for treating diseases related to venous function deficiency and/or inflammatory oedema, is disclosed. In general formula (I), A is a sulphur or oxygen atom or a radical R3N where R3 is a hydrogen atom, a C1-5 alkyl radical or an optionally substituted aromatic or heteroaromatic ring; each of X1, X2, X3 and X4 is independently a carbon atom or a nitrogen atom; R1 is a C1-5 alkyl radical, an optionally substituted aromatic ring or an optionally substituted heteroaromatic ring having one or more heteroatoms; and R2 is a hydrogen atom or a C1-5 alkyl radical.