DERIVES DE LA 1-((1,1-DIPHENYL)-1-ALCENYL)-PIPERAZINE, PROCEDE D'OBTENTION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

The invention relates to 1-[(1,1-diphenyl)-1-alkenyl]piperazine derivatives corresponding to general formula I: (I) in which R1, R2, R3, R4 and R5, which are identical or different, represent a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkoxy group or the tri...

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Hauptverfasser: ANDRE BUZAS, ROLAND OLLIVIER
Format: Patent
Sprache:fre
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Zusammenfassung:The invention relates to 1-[(1,1-diphenyl)-1-alkenyl]piperazine derivatives corresponding to general formula I: (I) in which R1, R2, R3, R4 and R5, which are identical or different, represent a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkoxy group or the trifluoromethyl group; n is an integer between 1 and 3; m is an integer from 0 to 3; Z represents a hydrogen atom, a lower alkyl group or an aryl group of the formula: in which R6 has the same meaning as R1, R2, R3 or R4; and A is an oxygen atom or a group and to their pharmaceutically acceptable salts. Application: pharmeutical compositions with antidepressant properties.