Anti-melanoma vaccine

Description of peptides or proteins which relate to an antigen associated with a melanoma. They are produced in large quantity by recombinant DNA techniques and/or by methods of chemical synthesis. The peptides or proteins can be used as immunogens in vaccine formulations which are capable of induci...

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Bibliographische Detailangaben
1. Verfasser: JOSEPH P. BROWN, CHARLES D. ESTIN, GREGORY D. PLOWMAN, TIMOTHY M. ROSE, KARL E. HELLSTROM, INGEGERD HELLSTROM, ANTHONY F. PURCHIO, SHIU-LOK HU ET SRIDHAR PENNATHUR
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Sprache:eng ; fre
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Zusammenfassung:Description of peptides or proteins which relate to an antigen associated with a melanoma. They are produced in large quantity by recombinant DNA techniques and/or by methods of chemical synthesis. The peptides or proteins can be used as immunogens in vaccine formulations which are capable of inducing an immune response and which selectively destroy melanoma cells of a vaccinated individual. When the peptides or proteins are expressed by a recombinant virus, it is possible to prepare vaccine formulations of inactivated or live viruses. DESCRIPTION DE PEPTIDES OU DE PROTEINES RELATIFS A UN ANTIGENE ASSOCIE A UN MELANOME. ON LES PRODUIT EN GRANDE QUANTITE PAR DES TECHNIQUES DE RECOMBINAISON DU DNA ETOU PAR DES METHODES DE SYNTHESE CHIMIQUE. ON PEUT UTILISER LES PEPTIDES OU PROTEINES COMME IMMUNOGENES DANS DES FORMULATIONS DE VACCIN QUI PEUVENT INDUIRE UNE REPONSE IMMUNITAIRE ET QUI DETRUISENT SELECTIVEMENT DES CELLULES DE MELANOME D'UN INDIVIDU VACCINE. LORSQUE LES PEPTIDES OU PROTEINES SONT EXPRIMES PAR UN VIRUS RECOMBINE, ON PEUT PREPARER DES FORMULATIONS DE VACCIN DE VIRUS INACTIVES OU VIVANTS.