NOUVEAUX DERIVES CEPHEM, PROCEDE POUR LA PREPARATION DE CES NOUVEAUX COMPOSES, COMPOSITIONS PHARMACEUTIQUES CONTENANT AU MOINS UN DE CES COMPOSES ET INTERMEDIAIRES DE SYNTHESE POUR LEUR PREPARATION

7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(substituted)-iminoacetamido]-3 -[3-(quaternaryammonio)-1 - propen-1-yl]-3-cephem-4-carboxylates of the formula in which R and R are as defined herein and is a quaternary ammonio group as defined herein, and salts, solvates, hydrates and esters thereof, are pot...

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1. Verfasser:	HARUHIRO YAMASHITA, MASAHISA OKA, TAKAYUKI NAITO ET JUN OKUMURA
Format:	Patent
Sprache:	fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(substituted)-iminoacetamido]-3 -[3-(quaternaryammonio)-1 - propen-1-yl]-3-cephem-4-carboxylates of the formula in which R and R are as defined herein and is a quaternary ammonio group as defined herein, and salts, solvates, hydrates and esters thereof, are potent antibacterial agents. Processes for their preparation and intermediates in such processes are described.