Mixed carboxylatoplatinum(II) complexes and process for the preparation of said complexes

The invention relates to the chemical complexes. The mixed complexes which form the subject of the invention are new products characterised in that they correspond to the general formula: R being tetrahydrofurfuryl or a cyclo-CnR''2n-1, R'' representing H, an alkyl or a hydroxyl...

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Bibliographische Detailangaben
1. Verfasser: P. A. CHELTSOV-BEBUTOV, A. N. KRAVCHENKO, R. N. SCHELOKOV, A. L. KONOVALOVA, M. A. PRESNOV ET V. B. IVANOV
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to the chemical complexes. The mixed complexes which form the subject of the invention are new products characterised in that they correspond to the general formula: R being tetrahydrofurfuryl or a cyclo-CnR''2n-1, R'' representing H, an alkyl or a hydroxyl group, n being equal to an integer from 3 to 6 and R' being -CH2-, -CH2-CH2-, -CH(OH)-, -CH(OH)-CH2- or -CH(OH)-CH(OH)-. The complexes in question in particular display anticancer effects. L'INVENTION CONCERNE LES COMPLEXES CHIMIQUES.LES COMPLEXES MIXTES FAISANT L'OBJET DE L'INVENTION SONT DES PRODUITS NOUVEAUX CARACTERISES EN CE QU'ILS REPONDENT A LA FORMULE GENERALE:(CF DESSIN DANS BOPI)R ETANT LE TETRAHYDROFURFURYLE OU UN CYCLO-CR-, R REPRESENTANT H, UN ALCOYLE, UN GROUPE HYDROXYLE, N ETANT EGAL A UN NOMBRE ENTIER DE 3 A 6, R ETANT -CH-, -CH-CH-, -CH(OH)-, -CH(OH)-CH-, -CH(OH)-CH(OH)-.LES COMPLEXES EN QUESTION MANIFESTENT NOTAMMENT DES EFFETS ANTICANCEREUX.