TRIAZOLOPYRIDIMIDINES NOUVELLES ET PROCEDE POUR LEUR FABRICATION

A.TRIAZOLOPYRIMIDINES NOUVELLES ET PROCEDE POUR LEUR FABRICATION.B.COMPOSES NOUVEAUX CARACTERISES EN CE QU'ILS SONT CONSTITUES PAR DES S-TRIAZOLO(1,5-A)PYRIMIDINES REPONDANT A LA FORMULE GENERALE I SUIVANTE:(CF DESSIN DANS BOPI)OU LES SUBSTITUANTS ONT LES SIGNIFICATIONS SUIVANTE:R ET R PEUVENT...

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1. Verfasser: MARTINA BALLNUS, ERNST TENOR, ECKEHARD THOMAS, RUDI PASCHE, HANS-JURGEN MEST, HANS-ULRICH BLOCK, PETER MENTZ ET INGRID HEINROCH
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description A.TRIAZOLOPYRIMIDINES NOUVELLES ET PROCEDE POUR LEUR FABRICATION.B.COMPOSES NOUVEAUX CARACTERISES EN CE QU'ILS SONT CONSTITUES PAR DES S-TRIAZOLO(1,5-A)PYRIMIDINES REPONDANT A LA FORMULE GENERALE I SUIVANTE:(CF DESSIN DANS BOPI)OU LES SUBSTITUANTS ONT LES SIGNIFICATIONS SUIVANTE:R ET R PEUVENT ETRE UN ATOME DE H, UN GROUPE ALCOYL DONT LA LONGUEUR DE CHAINE EST C A C, OU UN ATOME D'HALOGENE- R EST UN GROUPE ALCOYL, LINEAIRE OU RAMIFIE D'UNE LONGUEUR DE CHAINE DE C A C,- R ET R SONT UN ATOME DE H, UN GROUPE ALCOYL LINEAIRE OU RAMIFIE D'UNE LONGUEUR DE CHAINE DE C A C, R ET R;C.L'INVENTION CONCERNE DES TRIAZOLOPYRIMIDINES NOUVELLES ET PROCEDE POUR LEUR FABRICATION. s-triazolo(1,5-a)pyrimidine compounds of the Formula (I> wherein R2 and R3 are the same or different and represent an H atom, a C1 to C3 alkyl group or a halogen atom; R4 represents a straight-chain or branched-chain C4 to C9 alkyl group, an aralkyl group substituted by one or more C1 to C3 alkoxy or alkyl groups; 2,5-dioxaheptyl or 3-oxahexyl residues; R5 represents an H atom, a C1 to C3 alkyl group, a hydroxyethyl group or a hydroxypropyl group; R6 and R7 are the same or different and represent an H atom, a straight-chain or branched-chain C1 to C5 alkyl group, or R6 and R7 together complete a cycloaliphatic ring, the substituents in positions 5 and 7 optionally being mutually exchanged, and the pharmaceutically acceptable salts thereof, their preparation and pharmaceutical compositions comprising them are disclosed as therapeutic aids for cardio-circulatory disorder.
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wherein R2 and R3 are the same or different and represent an H atom, a C1 to C3 alkyl group or a halogen atom; R4 represents a straight-chain or branched-chain C4 to C9 alkyl group, an aralkyl group substituted by one or more C1 to C3 alkoxy or alkyl groups; 2,5-dioxaheptyl or 3-oxahexyl residues; R5 represents an H atom, a C1 to C3 alkyl group, a hydroxyethyl group or a hydroxypropyl group; R6 and R7 are the same or different and represent an H atom, a straight-chain or branched-chain C1 to C5 alkyl group, or R6 and R7 together complete a cycloaliphatic ring, the substituents in positions 5 and 7 optionally being mutually exchanged, and the pharmaceutically acceptable salts thereof, their preparation and pharmaceutical compositions comprising them are disclosed as therapeutic aids for cardio-circulatory disorder.</description><edition>4</edition><language>fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; 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wherein R2 and R3 are the same or different and represent an H atom, a C1 to C3 alkyl group or a halogen atom; R4 represents a straight-chain or branched-chain C4 to C9 alkyl group, an aralkyl group substituted by one or more C1 to C3 alkoxy or alkyl groups; 2,5-dioxaheptyl or 3-oxahexyl residues; R5 represents an H atom, a C1 to C3 alkyl group, a hydroxyethyl group or a hydroxypropyl group; R6 and R7 are the same or different and represent an H atom, a straight-chain or branched-chain C1 to C5 alkyl group, or R6 and R7 together complete a cycloaliphatic ring, the substituents in positions 5 and 7 optionally being mutually exchanged, and the pharmaceutically acceptable salts thereof, their preparation and pharmaceutical compositions comprising them are disclosed as therapeutic aids for cardio-circulatory disorder.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TRIAZOLOPYRIDIMIDINES NOUVELLES ET PROCEDE POUR LEUR FABRICATION
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