PROCEDE POUR LA PREPARATION DE COMPOSITIONS PHARMACEUTIQUES A LIBERATION SOUTENUE, AYANT UNE FORTE TENEUR EN INGREDIENT ACTIF

The invention relates to a process for the preparation of sustained-release pharmaceutical compositions having a high content of active ingredient. The process comprises the coating of particles of active ingredients with a water-insoluble polymer, followed by the mixing of crystals coated with a di...

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Bibliographische Detailangaben
Hauptverfasser:	BOR ILONA, BAUMGARTNER NEE, FEKETE PAL, PAL FEKETE, TIBOR KOVACS, DENES BEZZEGH, ILONA BOR, NEE BAUMGARTNER, ZOLTAN TOTH, KATALIN ZUKOVICS, NEE SUMEG ET EVA TAMAS, SUMEG NEE, KOVACS TIBOR, TOTH ZOLTAN, TAMAS EVA, ZUKOVICS KATALIN, BEZZEGH DENES
Format:	Patent
Sprache:	fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The invention relates to a process for the preparation of sustained-release pharmaceutical compositions having a high content of active ingredient. The process comprises the coating of particles of active ingredients with a water-insoluble polymer, followed by the mixing of crystals coated with a disintegrating agent capable of swelling in an aqueous medium and the compression of the mixture into tablets. Application: pharmaceutical industry. LA PRESENTE INVENTION EST RELATIVE A UN PROCEDE POUR LA PREPARATION DE COMPOSITIONS PHARMACEUTIQUES A LIBERATION SOUTENUE, AYANT UNE FORTE TENEUR EN INGREDIENT ACTIF. LE PROCEDE SE CARACTERISE EN CE QU'IL COMPREND L'ENDUCTION DE PARTICULES D'INGREDIENTS ACTIFS AVEC UN POLYMERE INSOLUBLE DANS L'EAU, PUIS LE MELANGE DE CRISTAUX ENDUITS AVEC UN AGENT DE DESAGREGATION CAPABLE DE GONFLER EN MILIEU AQUEUX ET LA COMPRESSION DU MELANGE EN COMPRIMES. APPLICATION: INDUSTRIE PHARMACEUTIQUE.