1,25-DIHYDROXYVITAMINES D2 ET PROCEDES POUR LES PREPARER

1,25-DIHYDROXYVITAMINES D2 ET PROCEDES POUR LES PREPARER

The invention is directed to the preparation of hydroxylated compounds of the vitamin D2 series and specifically to a process for synthesizing 1 alpha ,25-dihydroxyvitamin D2, 1 beta ,25-dihydroxyvitamin D2, their corresponding 5,6-trans isomers and the C-24 epimers of these compounds. The hydroxyla...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: HECTOR F. DELUCA, HEINRICH K. SCHNOES, RAFAL R. SICINSKI ET YOKO TANAKA
Format: Patent
Sprache:fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Beschreibung
Zusammenfassung:The invention is directed to the preparation of hydroxylated compounds of the vitamin D2 series and specifically to a process for synthesizing 1 alpha ,25-dihydroxyvitamin D2, 1 beta ,25-dihydroxyvitamin D2, their corresponding 5,6-trans isomers and the C-24 epimers of these compounds. The hydroxylated vitamin D2 compounds obtained exhibit vitamin D-like activity and can be substituted for vitamin D3 or various of its known metabolites where such compounds are applied.