3-(HYDRAZINIUM-2,2,2-TRISUBSTITUES)PROPIONATES

LA PRESENTE INVENTION CONCERNE DE NOUVEAUX COMPOSES CHIMIQUES.LESDITS COMPOSES SONT CARACTERISES EN CE QUE CE SONT DES 3-(HYDRAZINIUM-2,2,2-TRISUBSTITUES) PROPIONATES REPONDANT A LA FORMULE GENERALE:(CF DESSIN DANS BOPI)DANS LAQUELLE R, R, R DESIGNENT UN ALCOYLE, UN ALCOYLE SUBSTITUE, UN ARYLE SUBST...

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1. Verfasser:	GUNAR ARVIDOVICH BREMANIS, IVARS YANOVICH KALVINSH, IRENE
Format:	Patent
Sprache:	fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRAPPING
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Zusammenfassung:	LA PRESENTE INVENTION CONCERNE DE NOUVEAUX COMPOSES CHIMIQUES.LESDITS COMPOSES SONT CARACTERISES EN CE QUE CE SONT DES 3-(HYDRAZINIUM-2,2,2-TRISUBSTITUES) PROPIONATES REPONDANT A LA FORMULE GENERALE:(CF DESSIN DANS BOPI)DANS LAQUELLE R, R, R DESIGNENT UN ALCOYLE, UN ALCOYLE SUBSTITUE, UN ARYLE SUBSTITUE OU NON SUBSTITUE, UN ARALCOYLE OU UN ALCOYLE INSATURE; R, R DESIGNENT H OU UN ALCOYLE INFERIEUR; N 0 A 2, SAUF DANS LE CAS OU R, R, R DESIGNENT UN METHYLE, R, R DESIGNENT H.LES COMPOSES REVENDIQUES EXERCENT UNE ACTIVITE HYPOTENSIVE ET ANTIARYTHMIQUE ET TROUVENT DES APPLICATIONS EN MEDECINE. Novel compounds, viz. 3-(2,2,2-trisubstituted hydrazinium) propionates have the following general formula: wherein R1, R2 and R3 are an alkyl, a substituted alkyl, a substituted or unsubstituted aryl, an aralkyl or an unsaturated alkyl; R4, R5 are hydrogen or a lower alkyl; n is 0 to 2, except for the case where R1, R2 and R3 are methyl, R4 and R5 are not hydrogen. The compounds of the present invention possess both hypotensive and antiarrhythmic activity and are useful in medicine.