MATERIAU DE SUTURE CHIRURGICAL RESORBABLE A BASE DE MONOCARBOXYLCELLULOSE ET PROCEDE DE PREPARATION DUDIT MATERIAU

L'INVENTION CONCERNE LA FABRICATION DE MATIERES RESORBABLES DANS LES MILIEUX BIOLOGIQUES.LE MATERIAU DE SUTURE FAISANT L'OBJET DE L'INVENTION EST CARACTERISE EN CE QU'IL EST A BASE DE MONOCARBOXYLCELLULOSE DE FORMULE GENERALE:(CF DESSIN DANS BOPI)OU M EST LE DEGRE DE POLYMERISATION DE LA CELLULOSE DE DEPART, DE 250 A 3300; P LA FRACTION MOLAIRE DES CYCLES D-GLUCOPYRANNOSE DANS UNE PERIODE DU POLYMERE, DE 0,95 A 0,05; Q LA FRACTION MOLAIRE DES CYCLES DE L'ACIDE D-ANHYDROGLUCURONIQUE, DE 0,05 A 0,95; S LA FRACTION MOLAIRE DU FRAGMENT DE COMPLEXE DE L'ACIDE D-ANHYDROGLUCURONIQUE, DU METAL ET DU COORDINAT, DE 0,03 A 0,55; ME UN METAL DE TRANSITION; N LA VALENCE DU METAL DE TRANSITION; K L'INDICE DE COORDINATION DU METAL DE TRANSITION 4; LIG, LES LIGANDS POLYDENTANTS; DENT, LA DENTATION DES LIGANDS 2.LE MATERIAU EN QUESTION EST DESTINE A LA SUTURE DE TISSUS BIOLOGIQUES ET PEUT ETRE UTILISE NOTAMMENT EN MEDECINE, EN BIOLOGIE ET DANS LA PRATIQUE VETERINAIRE. An absorbable surgical suture material based on monocarboxycellulose having the general formula +TR where: m is a degree of polymerization of the initial cellulose from 250 to 3,300; p is a molar fraction of D-glucopyranose cycles in one polymer period from 0.95 to 0.05; q is a molar fraction of cycles of d-anhydroglucuronic acid from 0.05 to 0.95; S is a molar fraction of the complex fragment of D-anhydroglucuronic acid, metal, and ligand from 0.03 to 0.55; Me is a transition metal; n is a valence of the transition metal; k is a coordination number of the transition metal >/=4; Lig is polydentate ligands; Dent is a dentation of the ligands >/=2. A method for producing said material consists in that cellulose threads are first threaded with nitrogen oxides, then for 0.5 to 2.0 hours treated with a 0.5-2.0-percent solution of a salt of a transition metal with a coordination number not less than 4 in a suitable solvent, and after this treated for 0.5 to 2.0 hours with a 1.0-2.0-percent solution of a polydentate complexing agent in a suitable solvent.