AMIDO-AMINOACIDES SUBSTITUES SUR N ET LEUR PROCEDE DE PREPARATION

Compounds of the formula wherein R and R9 are independently hydroxy or lower alkoxy, R1 and R2 are hydrogen or lower alkyl, aryl-lower alkyl having from 7 to 12 carbon atoms, or heterocyclic-lower alkyl having from 6 to 12 carbon atoms, R3, R4, R5, R7 and R8 are hygrogen or lower alkyl, R6 is cycloa...

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Bibliographische Detailangaben
1. Verfasser:	RAYMOND D. YOUSSEFYEH, JERRY W. SKILES, JOHN T. SUH ET HOWARD JONES
Format:	Patent
Sprache:	fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Compounds of the formula wherein R and R9 are independently hydroxy or lower alkoxy, R1 and R2 are hydrogen or lower alkyl, aryl-lower alkyl having from 7 to 12 carbon atoms, or heterocyclic-lower alkyl having from 6 to 12 carbon atoms, R3, R4, R5, R7 and R8 are hygrogen or lower alkyl, R6 is cycloalkly having from 3 to 20 carbon atoms, aryl or aryl-lower alkyl, and the aryl group contains from 6 to 10 carbon atoms, and their pharmaceutically acceptable, nontoxic acid addition salts and where R or R9 or both are hydroxy, their pharmaceutically acceptable, nontoxic basic salts possess antihypertensive activity.