Diuretic phenylthio-piperazine derivs. - prepd. from phenylthio-phthalimide and tri:fluoromethyl-thio-piperazine

Diuretic phenylthio-piperazine derivs. - prepd. from phenylthio-phthalimide and tri:fluoromethyl-thio-piperazine

Phenylthio piperazines of formula (I) are new (where n = 0, 1 or 2). (I) are prepd. by reaction of a phenyl piperazine (II) with 2-phenyl thiophthalimide (III). The reaction is carried out in a non-ionising solvent, such as toluene, pref. at the boiling point. COMPOSES REPONDANT A LA FORMULE GENERAL...

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Bibliographische Detailangaben
1. Verfasser: HENRY NAJER
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Phenylthio piperazines of formula (I) are new (where n = 0, 1 or 2). (I) are prepd. by reaction of a phenyl piperazine (II) with 2-phenyl thiophthalimide (III). The reaction is carried out in a non-ionising solvent, such as toluene, pref. at the boiling point. COMPOSES REPONDANT A LA FORMULE GENERALE:(CF DESSIN DANS BOPI)DANS LAQUELLE LE RADICAL S(O)CF DANS LEQUEL N 0, 1 OU 2 OCCUPE UNE POSITION QUELCONQUE SUR LE NOYAU PHENYLE.APPLICATION EN THERAPEUTIQUE.