DERIVES DE GLYOXAL-2-OXIME ET LEUR PROCEDE DE PREPARATION

Nouveaux dérivés de glyoxal-2-oxime répondant à la formule chimique : Novel derivatives of glyoxal-2-oxim represented by the chemical formula [I] wherein R is hydrogen or a lower alkyl or phenyl group, are provided in accordance with the present invention. These derivatives are prepared by reacting...

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1. Verfasser: TAKAJI HONNA, MOTOAKI TANAKA, SYOZO YAMADA ET HIDEKAZU MIYAKE
Format: Patent
Sprache:fre
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Zusammenfassung:Nouveaux dérivés de glyoxal-2-oxime répondant à la formule chimique : Novel derivatives of glyoxal-2-oxim represented by the chemical formula [I] wherein R is hydrogen or a lower alkyl or phenyl group, are provided in accordance with the present invention. These derivatives are prepared by reacting the corresponding isoxazole-5-carbaldehyde with nitromethane in the presence of a metal alkoxide, or the corresponding 5-acetylisoxazole with a nitrate. They have anti-inflammatory and/or analgesic activities.