2-Piperidino-4-amino-quinazoline derivs. - useful as antihypertensives

2-Piperidino-4-amino-quinazoline derivs. - useful as antihypertensives

Quinazoline derivs. of formula (I) and their acid addition salts are new: (where X is CH2, CHOH or CO. R2 = furyl or tetrahydrofuryl). (I) are made by reacting the corresp. 2-haloquinazoline with a 4-XR2-substd. piperidine. (I) are antihypertensives useful in human and veterinary medicine. Their int...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: PHILIPPE MICHEL JACQUES MANOURY
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator PHILIPPE MICHEL JACQUES MANOURY
description Quinazoline derivs. of formula (I) and their acid addition salts are new: (where X is CH2, CHOH or CO. R2 = furyl or tetrahydrofuryl). (I) are made by reacting the corresp. 2-haloquinazoline with a 4-XR2-substd. piperidine. (I) are antihypertensives useful in human and veterinary medicine. Their intraperitoneal LD50 is 10-300 mg/kg (rat) and they are highly soluble in water so can be administered parenterally. GUANIDINES CYCLISEES REPONDANT A LA FORMULE GENERALE:(CF DESSIN DANS BOPI)DANS LAQUELLE:X REPRESENTE UN CHAINON CH, CHOH OU CO; ETR REPRESENTE UN RADICAL FURYLE OU TETRAHYDROFURYLE AINSI QUE LEURS SELS D'ADDITION AUX ACIDES PHARMACEUTIQUEMENT ACCEPTABLES.APPLICATION EN THERAPEUTIQUE.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_FR2408603A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>FR2408603A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_FR2408603A23</originalsourceid><addsrcrecordid>eNrjZHAz0g3ILEgtykzJzMvXNdFNzAXRhaWZeYlV-TmZeakKKUDJsmI9BV2F0uLUtNIchcRihcS8ksyMSqC2ktS84syy1GIeBta0xJziVF4ozc2g4OYa4uyhm1qQH59aXJCYnJqXWhLvFmRkYmBhZmDsaGRMhBIAlFMy8A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>2-Piperidino-4-amino-quinazoline derivs. - useful as antihypertensives</title><source>esp@cenet</source><creator>PHILIPPE MICHEL JACQUES MANOURY</creator><creatorcontrib>PHILIPPE MICHEL JACQUES MANOURY</creatorcontrib><description>Quinazoline derivs. of formula (I) and their acid addition salts are new: (where X is CH2, CHOH or CO. R2 = furyl or tetrahydrofuryl). (I) are made by reacting the corresp. 2-haloquinazoline with a 4-XR2-substd. piperidine. (I) are antihypertensives useful in human and veterinary medicine. Their intraperitoneal LD50 is 10-300 mg/kg (rat) and they are highly soluble in water so can be administered parenterally. GUANIDINES CYCLISEES REPONDANT A LA FORMULE GENERALE:(CF DESSIN DANS BOPI)DANS LAQUELLE:X REPRESENTE UN CHAINON CH, CHOH OU CO; ETR REPRESENTE UN RADICAL FURYLE OU TETRAHYDROFURYLE AINSI QUE LEURS SELS D'ADDITION AUX ACIDES PHARMACEUTIQUEMENT ACCEPTABLES.APPLICATION EN THERAPEUTIQUE.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>1979</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19790608&amp;DB=EPODOC&amp;CC=FR&amp;NR=2408603A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19790608&amp;DB=EPODOC&amp;CC=FR&amp;NR=2408603A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PHILIPPE MICHEL JACQUES MANOURY</creatorcontrib><title>2-Piperidino-4-amino-quinazoline derivs. - useful as antihypertensives</title><description>Quinazoline derivs. of formula (I) and their acid addition salts are new: (where X is CH2, CHOH or CO. R2 = furyl or tetrahydrofuryl). (I) are made by reacting the corresp. 2-haloquinazoline with a 4-XR2-substd. piperidine. (I) are antihypertensives useful in human and veterinary medicine. Their intraperitoneal LD50 is 10-300 mg/kg (rat) and they are highly soluble in water so can be administered parenterally. GUANIDINES CYCLISEES REPONDANT A LA FORMULE GENERALE:(CF DESSIN DANS BOPI)DANS LAQUELLE:X REPRESENTE UN CHAINON CH, CHOH OU CO; ETR REPRESENTE UN RADICAL FURYLE OU TETRAHYDROFURYLE AINSI QUE LEURS SELS D'ADDITION AUX ACIDES PHARMACEUTIQUEMENT ACCEPTABLES.APPLICATION EN THERAPEUTIQUE.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1979</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAz0g3ILEgtykzJzMvXNdFNzAXRhaWZeYlV-TmZeakKKUDJsmI9BV2F0uLUtNIchcRihcS8ksyMSqC2ktS84syy1GIeBta0xJziVF4ozc2g4OYa4uyhm1qQH59aXJCYnJqXWhLvFmRkYmBhZmDsaGRMhBIAlFMy8A</recordid><startdate>19790608</startdate><enddate>19790608</enddate><creator>PHILIPPE MICHEL JACQUES MANOURY</creator><scope>EVB</scope></search><sort><creationdate>19790608</creationdate><title>2-Piperidino-4-amino-quinazoline derivs. - useful as antihypertensives</title><author>PHILIPPE MICHEL JACQUES MANOURY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_FR2408603A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>1979</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>PHILIPPE MICHEL JACQUES MANOURY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PHILIPPE MICHEL JACQUES MANOURY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>2-Piperidino-4-amino-quinazoline derivs. - useful as antihypertensives</title><date>1979-06-08</date><risdate>1979</risdate><abstract>Quinazoline derivs. of formula (I) and their acid addition salts are new: (where X is CH2, CHOH or CO. R2 = furyl or tetrahydrofuryl). (I) are made by reacting the corresp. 2-haloquinazoline with a 4-XR2-substd. piperidine. (I) are antihypertensives useful in human and veterinary medicine. Their intraperitoneal LD50 is 10-300 mg/kg (rat) and they are highly soluble in water so can be administered parenterally. GUANIDINES CYCLISEES REPONDANT A LA FORMULE GENERALE:(CF DESSIN DANS BOPI)DANS LAQUELLE:X REPRESENTE UN CHAINON CH, CHOH OU CO; ETR REPRESENTE UN RADICAL FURYLE OU TETRAHYDROFURYLE AINSI QUE LEURS SELS D'ADDITION AUX ACIDES PHARMACEUTIQUEMENT ACCEPTABLES.APPLICATION EN THERAPEUTIQUE.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre
recordid cdi_epo_espacenet_FR2408603A2
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title 2-Piperidino-4-amino-quinazoline derivs. - useful as antihypertensives
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T03%3A33%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=PHILIPPE%20MICHEL%20JACQUES%20MANOURY&rft.date=1979-06-08&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EFR2408603A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true