DERIVES DE BENZIMIDAZOLE CONTENANT DU SOUFRE, PROCEDE POUR LEUR PREPARATION ET INTERMEDIAIRES UTILES POUR LEUR PRODUCTION
L'invention concerne des composés chimiques nouveaux. Il s'agit de composés de formule : A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R...
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| creator | CSABA GONCZI, DEZSO KORBONITS, PAL KISS, ENDRE PALOSI, GERGELY HEJA, GYORGYNE SZVOBODA, GABORNE CSER, TIBORNE SZOMOR, GYORGY KORMOCZI ET ANDRAS KELEMEN |
| description | L'invention concerne des composés chimiques nouveaux. Il s'agit de composés de formule :
A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl; or pharmaceutically acceptable salts thereof comprises subjecting a bis compound of the formula: to reduction to cleave the disulfide linkage and where R4 is other then hydrogen, subsequent reaction of the mercapto group. Intermediate compounds and a process for preparing same are also disclosed. |
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A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl; or pharmaceutically acceptable salts thereof comprises subjecting a bis compound of the formula: to reduction to cleave the disulfide linkage and where R4 is other then hydrogen, subsequent reaction of the mercapto group. Intermediate compounds and a process for preparing same are also disclosed.</description><language>fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; AGRICULTURE ; ANIMAL HUSBANDRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; CHEMISTRY ; FISHING ; FORESTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HUNTING ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; TRAPPING</subject><creationdate>1979</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19790323&DB=EPODOC&CC=FR&NR=2401144A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19790323&DB=EPODOC&CC=FR&NR=2401144A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CSABA GONCZI, DEZSO KORBONITS, PAL KISS, ENDRE PALOSI, GERGELY HEJA, GYORGYNE SZVOBODA, GABORNE CSER, TIBORNE SZOMOR, GYORGY KORMOCZI ET ANDRAS KELEMEN</creatorcontrib><title>DERIVES DE BENZIMIDAZOLE CONTENANT DU SOUFRE, PROCEDE POUR LEUR PREPARATION ET INTERMEDIAIRES UTILES POUR LEUR PRODUCTION</title><description>L'invention concerne des composés chimiques nouveaux. Il s'agit de composés de formule :
A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl; or pharmaceutically acceptable salts thereof comprises subjecting a bis compound of the formula: to reduction to cleave the disulfide linkage and where R4 is other then hydrogen, subsequent reaction of the mercapto group. Intermediate compounds and a process for preparing same are also disclosed.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</subject><subject>CHEMISTRY</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEST REPELLANTS OR ATTRACTANTS</subject><subject>PLANT GROWTH REGULATORS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>TRAPPING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1979</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNzLEKwjAUBdAuDqL-w_sABav9gZi84oM0L7wmHbqUInESLdTFvzeCg6PLvcu5d1m8DAp12IJBOKHrqSGjerYIml1Ap1wAE6HlWAtuwQtrzNRzFLCYwwt6JSoQO8AAlEfSoCFFkl9jIJvrl7OJ-qPXxeI63ua0-faqgBqDPu_S9BjSPI2XdE_PoZZDtS_LqlLl8Q_yBpQsOkc</recordid><startdate>19790323</startdate><enddate>19790323</enddate><creator>CSABA GONCZI, DEZSO KORBONITS, PAL KISS, ENDRE PALOSI, GERGELY HEJA, GYORGYNE SZVOBODA, GABORNE CSER, TIBORNE SZOMOR, GYORGY KORMOCZI ET ANDRAS KELEMEN</creator><scope>EVB</scope></search><sort><creationdate>19790323</creationdate><title>DERIVES DE BENZIMIDAZOLE CONTENANT DU SOUFRE, PROCEDE POUR LEUR PREPARATION ET INTERMEDIAIRES UTILES POUR LEUR PRODUCTION</title><author>CSABA GONCZI, DEZSO KORBONITS, PAL KISS, ENDRE PALOSI, GERGELY HEJA, GYORGYNE SZVOBODA, GABORNE CSER, TIBORNE SZOMOR, GYORGY KORMOCZI ET ANDRAS KELEMEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_FR2401144A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fre</language><creationdate>1979</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</topic><topic>CHEMISTRY</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEST REPELLANTS OR ATTRACTANTS</topic><topic>PLANT GROWTH REGULATORS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>TRAPPING</topic><toplevel>online_resources</toplevel><creatorcontrib>CSABA GONCZI, DEZSO KORBONITS, PAL KISS, ENDRE PALOSI, GERGELY HEJA, GYORGYNE SZVOBODA, GABORNE CSER, TIBORNE SZOMOR, GYORGY KORMOCZI ET ANDRAS KELEMEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CSABA GONCZI, DEZSO KORBONITS, PAL KISS, ENDRE PALOSI, GERGELY HEJA, GYORGYNE SZVOBODA, GABORNE CSER, TIBORNE SZOMOR, GYORGY KORMOCZI ET ANDRAS KELEMEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVES DE BENZIMIDAZOLE CONTENANT DU SOUFRE, PROCEDE POUR LEUR PREPARATION ET INTERMEDIAIRES UTILES POUR LEUR PRODUCTION</title><date>1979-03-23</date><risdate>1979</risdate><abstract>L'invention concerne des composés chimiques nouveaux. Il s'agit de composés de formule :
A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl; or pharmaceutically acceptable salts thereof comprises subjecting a bis compound of the formula: to reduction to cleave the disulfide linkage and where R4 is other then hydrogen, subsequent reaction of the mercapto group. Intermediate compounds and a process for preparing same are also disclosed.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRAPPING |
| title | DERIVES DE BENZIMIDAZOLE CONTENANT DU SOUFRE, PROCEDE POUR LEUR PREPARATION ET INTERMEDIAIRES UTILES POUR LEUR PRODUCTION |
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