DERIVES DE BENZIMIDAZOLE CONTENANT DU SOUFRE, PROCEDE POUR LEUR PREPARATION ET INTERMEDIAIRES UTILES POUR LEUR PRODUCTION
L'invention concerne des composés chimiques nouveaux. Il s'agit de composés de formule : A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R...
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Zusammenfassung: | L'invention concerne des composés chimiques nouveaux. Il s'agit de composés de formule :
A process for the preparation of anthelmintic compounds of the formula: wherein R1 is hydrogen or -COOR; R5 is C1 to C4 alkyl; R2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and R4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl; or pharmaceutically acceptable salts thereof comprises subjecting a bis compound of the formula: to reduction to cleave the disulfide linkage and where R4 is other then hydrogen, subsequent reaction of the mercapto group. Intermediate compounds and a process for preparing same are also disclosed. |
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