Cardenolide and bufadienolide derivs. of ajmaline - for use as cardioactive medicaments

Ajmaline derivs. of formula (I) (where R1 is a cardenolide or bufadienolide residue; X is halogen; R is H, acyl or alkyl, pref. with 1-5C), are new. Cpds. (I) have anti-arrhythmic and cardiotonic activity. A typical cpd. (I) is strophanthidine-3-O-acetyl-2'-N(b)-ajmaline bromide. In an example,...

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1. Verfasser:	IVAN FOMICH MAKAREVICH, YAROSLAV IVANOVICH KHADZHAI, VALERIA VLADIMIROVNA PAVLOVA ET ANASTASIA VIKTOROVNA NIKOLAEVA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
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