ACIDES 5-ALKOXY-PICOLINIQUES, PROCEDE POUR LEUR PREPARATION ET COMPOSITION ANTI-HYPERTENSIVE CONTENANT DES ACIDES 5-ALKOXY-PICOLINIQUE

L'invention a pour objet des acides 5-alkoxy-picoliniques et un procédé pour leurs préparation et composition antihypertensive contenant des acides 5-alkoxy-picoliniques. Ces acides 5-alkoxy-picoliniques, leurs sels et leurs esters, répondent à la formule (I) : 5-Alkoxy-picolinic acids and the salts and the esters thereof represented by the formula (I): (I) wherein R represents an alkyl group having 1 to 6 carbon atoms and M represents a hydrogen atom; a calcium atom; a sodium atom; a potassium atom; an aluminum atom; an unsubstituted phenyl group; a phenyl group substituted with one or more of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms or a halogen atom (such as a chlorine, bromine, iodine, etc., atom); a phthalidyl group; an alkoxyalkyl group wherein the alkyl moiety and the alkoxy moiety each has 1 to 4 carbon atoms; or an acyloxyalkyl group having the formula wherein R2 represents a hydrogen atom or a methyl group and R3 represents an alkyl group having 1 to 5 carbon atoms (such as a methyl, n-propyl, isobutyl, t-butyl, etc., group), an alkoxy group having 1 to 4 carbon atoms, a phenyl group, a phenyl group substituted with one or more of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms or a halogen atom (such as a chlorine, bromine, iodine, etc., atom) or an aralkyl group wherein the alkyl moiety has 1 to 3 carbon atoms, which are useful as anti-hypertensive agents, a process for preparing 5-alkoxy-picolinic acids and the salts and the esters thereof, and anti-hypertensive compositions containing the 5-alkoxy-picolinic acids and the salts and the esters thereof.