Nouveaux éthers des hormones oestrogenes
The invention comprises steroids of the general formula: wherein X represents an a -hydroxy group or a b -hydroxy a -alkyl grouping in which the alkyl group contains 1 to 3 carbon atoms and Y represents hydrogen or a hydroxy group, and the preparation thereof by reacting the corresponding free 3-hy...
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Zusammenfassung: | The invention comprises steroids of the general formula: wherein X represents an a -hydroxy group or a b -hydroxy a -alkyl grouping in which the alkyl group contains 1 to 3 carbon atoms and Y represents hydrogen or a hydroxy group, and the preparation thereof by reacting the corresponding free 3-hydroxy compound or the sodium or potassium salt thereof with a cyclopentyl halide in the presence of a basic condensing agent such as an alkaline hydroxide, carbonate or alcoholate. Pharmaceutical compositions having estrogenic activity contain one or more steroids of the above general formula and a non-toxic pharmaceutical carrier suitable for oral or parenteral administration. |
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