Temotsolomidin tehostaminen ihmisten kasvainsoluissa

The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O -benzylguanine.

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Bibliographische Detailangaben
Hauptverfasser: WATSON, AMANDA JEAN, FREEMAN, AZADEH ALISON, MARGISON, GEOFFREY PAUL, NEWLANDS, EDWARD STUART, BAER, JOHN COLIN, RAFFERTY, JOSEPH ANTHONY
Format: Patent
Sprache:fin ; swe
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Zusammenfassung:The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O -benzylguanine.