Menetelmä veteen liukenemattomien hyaluronihappogeelien ja -kalvojen valmistamiseksi

A method for making a water insouble bicompatible gel includes activating HA with an activating agent to form activated HA, and reacting the activated HA with a nucleophile, under conditions producing the water insoluble bicompatible gel. Also, a method for making a water insoluble biocompatible fil...

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Bibliographische Detailangaben
Hauptverfasser: FOX, ELLEN M, HAMILTON, RAYMOND G, WALTS, ALAN E, ACHARYA, RAKSHA A
Format: Patent
Sprache:fin ; swe
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Zusammenfassung:A method for making a water insouble bicompatible gel includes activating HA with an activating agent to form activated HA, and reacting the activated HA with a nucleophile, under conditions producing the water insoluble bicompatible gel. Also, a method for making a water insoluble biocompatible film includes providing a biocompatible gel made according to the above method, and drying the gel or compressing the gel under conditions permitting escape of water from the gel. Also, a water insoluble composition including HA is prepared without the use of any bifunctional or polyfunctional nucleophile.