Oligoribonukleotid- och ribozymanaloger med terminala 3'-3'- eller 5'-5'-bindningar

The invention relates to oligoribonucleotide analogues with terminal 3'-3' or 5'-5' internucleotide linkages. This modification stabilises the molecules modified in this way, including ribozymes, without adversely changing their properties, including catalytic activities where ap...

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Bibliographische Detailangaben
Hauptverfasser: ROESCH, RUDI, SELIGER, HEINZ HARTMUT, ORTIGAO, FLAVIO RAMALHO, KRIST, BERND, ROESCH, HANNELORE
Format: Patent
Sprache:fin
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Zusammenfassung:The invention relates to oligoribonucleotide analogues with terminal 3'-3' or 5'-5' internucleotide linkages. This modification stabilises the molecules modified in this way, including ribozymes, without adversely changing their properties, including catalytic activities where appropriate.