DERIVAT AV MAENSKLIG BFGF, DERAS ANALOGER OCH FOERFARANDE FOER DERAS FRAMSTAELLNING

Recombinant human basic fibroblast growth factors or functionally equivalent analogs thereof are provided in which at least one of the four cysteine amino acid residues is derivatized. Usually the two cysteines corresponding to those present in positions 69 and 87 of the 146 amino acid form of the n...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	CAUET, GILLES, NITTI, GIAMPAOLO, CACCIA, PAOLO, BERTOLERO, FEDERICO
Format:	Patent
Sprache:	fin
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Recombinant human basic fibroblast growth factors or functionally equivalent analogs thereof are provided in which at least one of the four cysteine amino acid residues is derivatized. Usually the two cysteines corresponding to those present in positions 69 and 87 of the 146 amino acid form of the natural human basic fibroblast growth factor are derivatized by moieties such as for example -CH2COOH or -CH2CONH2. Such derivatized recombinant human basic fibroblast growth factors may be used for the healing of wounds, ulcers or burns; regeneration of damaged neural tissues; aiding tissue transplant or healing bone graft; or revascularization of ischaemic tissues.