Menetelmä 1,4-dihydropyridiinijohdannaisten valmistamiseksi

Menetelmä 1,4-dihydropyridiinijohdannaisten valmistamiseksi

The invention is directed to processes for the preparation of dimethyl-1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-pyridine-3,5-dica rboxylate by reacting 1-methoxy-1-(2'-nitrophenyl)-N-(2'-nitrophenyl)methylene methanamie or 1-(2'-nitrophenyl)-N,N'-bis-(2'-nitrophenyl)...

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Bibliographische Detailangaben
Hauptverfasser: NAGY, K LM N, IMRE, J NOS, TOEMPE, PETER, BOZSING, D NIEL, POCZIK, @VA, M NDI, ATTILA, SIMONYI, ISTV N, TAJTHY NEE JUH SZ, @VA JUDIT, KOV NYI NEE LAX, GYOERGYI, ZALAV RI NEE DOSA, GYOERGYI, L~VAI, L SZLO, BECK, IV N, DINNY~S NEE NAGY, ILONA, KISS NEE BERTOK, ERZS~BET, MIKITE, GYULA, BENKO, P L, GOERG~NYI, FRIGYES, FURDYGA, @VA
Format: Patent
Sprache:fin ; swe
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention is directed to processes for the preparation of dimethyl-1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-pyridine-3,5-dica rboxylate by reacting 1-methoxy-1-(2'-nitrophenyl)-N-(2'-nitrophenyl)methylene methanamie or 1-(2'-nitrophenyl)-N,N'-bis-(2'-nitrophenyl) methylene methanediamine with methyl acetoacetate in the presence of an amine compound or by reacting the monomeric or trimeric from of 2-nitrobenzaldimine with methyl acetoacetate.