OLIGONUKLEOTIDANALOGER MED TERMINALA 3'-3'- ELLER 5'-5'-INTERNUKLEOTIDKOPPLINGAR

Therapeutically utilisable oligonucleotides of the formulae I and II are obtained by introducing terminal 3'-3' or 5'-5' linkages. These nuclease-stable compounds suppress the biological function of nucleic acids.

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Bibliographische Detailangaben
Hauptverfasser: FROEHLICH, ANJA, RAMALHO-ORTIGAO, JOSE FLAVIO, MONTENARH, MATTHIAS, SELIGER, HARTMUT, ROESCH, HANNELORE
Format: Patent
Sprache:fin
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Zusammenfassung:Therapeutically utilisable oligonucleotides of the formulae I and II are obtained by introducing terminal 3'-3' or 5'-5' linkages. These nuclease-stable compounds suppress the biological function of nucleic acids.