FOERFARANDE FOER FRAMSTAELLNING AV 14,15-SUBSTITUERADE LANOSTEROLER

FOERFARANDE FOER FRAMSTAELLNING AV 14,15-SUBSTITUERADE LANOSTEROLER

Lanosterols substituted in the 14 and/or 15 position(s) which are active in inhibiting lanosta-8,24-dien-3 beta -ol 14 alpha -methyl-demethylase activity, supressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity, decreasing cholesterol synthesis and reducing serum cholesterol level...

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Bibliographische Detailangaben
Hauptverfasser: KO, SOO SUNG, PAUL ROBERT JOHNSON, TRZASKOS, JAMES MICHAEL, STAM, SIMON HENDRIK, JOHNSON, PAUL ROBERT, MAGOLDA, RONALD LOUIS
Format: Patent
Sprache:fin
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Beschreibung
Zusammenfassung:Lanosterols substituted in the 14 and/or 15 position(s) which are active in inhibiting lanosta-8,24-dien-3 beta -ol 14 alpha -methyl-demethylase activity, supressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity, decreasing cholesterol synthesis and reducing serum cholesterol levels are disclosed.