HYDRAZONDERIVAT

Compound which is expressed by general formula given below, and which have an excellent cardiotonic action (I), wherein R' denotes halogen or cyano; n denotes 0, 1 or 2 (provided when n is 2, R' may differ from each other); R denotes hydrogen, thienyl, the radical expressed by formula (II)...

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Hauptverfasser: MURAKATA, MASATOSHI, ICHIMORI, TATSUHIKO, MOCHIZUKI, NOBUO, KUSASE, YOU, YOKOSUKA, IKUO, MAEDA, KUNIYASU
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Sprache:fin
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Zusammenfassung:Compound which is expressed by general formula given below, and which have an excellent cardiotonic action (I), wherein R' denotes halogen or cyano; n denotes 0, 1 or 2 (provided when n is 2, R' may differ from each other); R denotes hydrogen, thienyl, the radical expressed by formula (II), cycloalkyl which may be substituted by cyano, or aliphatic hydrocarbon radical which may be substituted by cyano, halogen, cycloalkyl, morpholino radical, the radical expressed by formula (III), (wherein each of r and r denotes hydrogen or C1-6 alkyl), the radical expressed by formula (IV) {wherein A denotes CH or N, X denotes hydroxy or C1-6 alkoxy; m denotes 0, 1 or 2 (provided that when m is 2, X may differ from each other)}, the radical expressed by the formula -Y-R1 {wherein Y denotes O or S(O)k (wherein k denotes 0, 1 or 2), R1 denotes hydrogen, C1-6 alkyl which may be substituted by cyano or C2-7 alkylcarbonyl} or the radical expressed by the formula -COR2 {wherein R2 denotes C1-6 alkyl, hydroxy, C1-6 alkoxy or the radical expressed by formula (V), (wherein each of r and r denotes hydrogen or C1-6 alkyl)}.